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PMID 28131081

36 NAD + -dependent cancer cell proliferation and metastasis Given the massive demand for NAD + to support the metabolism reprogramming, the genome integrity and gene transcription in tumorigenesis, cancer cells enhance the capacity of NAD + production through various pathways

In response to NO and peroxynitrite, MTs release Zn, which induces MTF-1, and this increases the expression of protective genes by scavenging some ROS and reactive nitrogen species [147]

Chaihu Guizhi Ganjiang decoction attenuates nonalcoholic steatohepatitis by enhancing intestinal barrier integrity and ameliorating Ppar mediated lipotoxicity